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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087582Generated: October 30, 2026

4-(Trifluoromethoxy)phenylhydrazine hydrochloride → 2-Methyl-N-[3-(1-{3-[2-phenyl-5-(trifluoromethoxy)-1H-indol-3-YL]propyl}-4-piperidinyl)phenyl]propanamide

https://huagongshe.com/reaction/2087582

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethoxy)phenylhydrazine hydrochlorideHCID 2777328—
Reactant2-methyl-N-(3-[1-(5-oxo-5-phenylpentyl)-4-piperidinyl]phenyl}propanamideHCID 22049393—
Product2-Methyl-N-[3-(1-{3-[2-phenyl-5-(trifluoromethoxy)-1H-indol-3-YL]propyl}-4-piperidinyl)phenyl]propanamideHCID 22049003—

Reaction Steps

Prepared by Procedure E and Scheme M using 2-methyl-N-{3-[1-(5-oxo-5-phenylpentyl)-4-piperidinyl]phenyl}propanamide and 1-[4-(trifluoromethoxy)phenyl]hydrazine hydrochloride: ESMS m/e: 564.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-bdf88a3ef2664dce9133c8fc286aede4
Source noteuspto-grants-2004_04