HRID2087595

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6578

Propanamide

C3H7NO

HCID2849445

2-Methoxyphenylhydrazine monohydrochloride

C7H11ClN2O

结构：CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccccc3)CC2)c1

HCID22049393

未命名化合物

PRODUCTS

生成物

结构：COc1cccc2c(CCCN3CCC(c4cccc(NC(=O)C(C)C)c4)CC3)c(-c3ccccc3)[nH]c12

HCID22049599

未命名化合物

PROCEDURE

实验过程

Prepared by Procedure E and Scheme M using 2-methyl-N-{3-[1-(5-oxo-5-phenylpentyl)-4-piperidinyl]phenyl)propanamide and 1-5-phenylpentyl)-4-piperidinyl]phenyl}propanamide and 1-(2-methoxyphenyl)hydrazine hydrochloride: ESMS m/e: 510.2 (M+H)+.

WORKUP

后处理

customPrepared by Procedure E and Scheme M

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ad13b612321a43adb416cc30b4ea40c0
来源数据集: uspto-grants-2004_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06727264B1
来源说明: uspto-grants-2004_04

反应 SMILES

[CH3:1][CH:2]([CH3:30])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][CH2:21][C:22](=O)[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4].C(N)(=O)CC.Cl.[CH3:37][O:38][C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][C:40]=1[NH:45]N>>[CH3:37][O:38][C:39]1[CH:44]=[CH:43][CH:42]=[C:41]2[C:40]=1[NH:45][C:22]([C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1)=[C:21]2[CH2:20][CH2:19][CH2:18][N:15]1[CH2:16][CH2:17][CH:12]([C:8]2[CH:7]=[C:6]([NH:5][C:3](=[O:4])[CH:2]([CH3:1])[CH3:30])[CH:11]=[CH:10][CH:9]=2)[CH2:13][CH2:14]1