Hydrazine, 1-naphthalenyl-, hydrochloride (1:1) → N-(3-{1-[3-(1H-Benzo[G]indol-3-YL)propyl]-4-piperidinyl}phenyl)-2-methylpropanamide

HRID 2087602Notes

Reaction equation

HRID 2087602 reaction equation
O1CCO[CH:2]1[CH2:6][CH2:7][CH2:8][CH2:9][N:10]1[CH2:15][CH2:14][CH:13]([C:16]2[CH:17]=[C:18]([NH:22][C:23](=[O:27])[CH:24]([CH3:26])[CH3:25])[CH:19]=[CH:20][CH:21]=2)[CH2:12][CH2:11]1.Cl.[C:29]1([NH:39]N)[C:38]2[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=2)[CH:32]=[CH:31][CH:30]=1>>[NH:39]1[C:29]2[C:30](=[CH:31][CH:32]=[C:33]3[CH:34]=[CH:35][CH:36]=[CH:37][C:38]3=2)[C:6]([CH2:7][CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH:13]([C:16]3[CH:17]=[C:18]([NH:22][C:23](=[O:27])[CH:24]([CH3:26])[CH3:25])[CH:19]=[CH:20][CH:21]=3)[CH2:14][CH2:15]2)=[CH:2]1

Participants

3

Reactant 2

HCID 519949Hydrazine, 1-naphthalenyl-, hydrochloride (1:1)HCID 22048802N-(3-{1-[4-(1,3-dioxolan-2-yl)butyl]4-piperidinyl}phenyl)-2-methylpropanamide

Product 1

HCID 22049168N-(3-{1-[3-(1H-Benzo[G]indol-3-YL)propyl]-4-piperidinyl}phenyl)-2-methylpropanamide

Procedure

Prepared by Procedure H and Scheme S using N-(3-{1-[4-(1,3-dioxolan-2-yl)butyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 1-(1-naphthyl)hydrazine hydrochloride: ESMS 454.2 m/e: (M+H)+.

Workup

  1. customPrepared by Procedure H and Scheme S

Sources & evidence

ORD record
ord-12f07e25ecc942249e44ca765d213a7d
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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