1-Iodo-4-nitrobenzene → 6-Chloro-1-(4-nitrophenyl)-1H-indole

HRID 2087618Notes

Reaction equation

HRID 2087618 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[CH:4][CH:3]=1.I[C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[CH:14][CH:13]=1>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][N:8]2[C:12]2[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[CH:14][CH:13]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 124951-Iodo-4-nitrobenzeneHCID 871116-Chloroindole

Product 1

HCID 220491566-Chloro-1-(4-nitrophenyl)-1H-indole

Procedure

Prepared by Procedure C and Scheme O using 6-chloro-1H-indole and 1-iodo-4-nitrobenzene: ESMS m/e: 272.6 (M+H)+.

Workup

  1. customPrepared by Procedure C and Scheme O

Sources & evidence

ORD record
ord-7048b738f99443e69fd28764a880b3f2
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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