3-Iodotoluene → 6-Chloro-1-(3-methylphenyl)-1H-indole

HRID 2087620Notes

Reaction equation

HRID 2087620 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[CH:4][CH:3]=1.I[C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH3:18])[CH:13]=1>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][N:8]2[C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([CH3:18])[CH:13]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 122683-IodotolueneHCID 871116-Chloroindole

Product 1

HCID 220495436-Chloro-1-(3-methylphenyl)-1H-indole

Procedure

Prepared by Procedure C and Scheme O using 6-chloro-1H-indole and 1-iodo-3-methylbenzene: ESMS m/e: 241.9 (M+H)+.

Workup

  1. customPrepared by Procedure C and Scheme O

Sources & evidence

ORD record
ord-90e24f16fe5c456b884a1179780fe08e
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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