Iodobenzene → 1-Phenyl-6-(trifluoromethyl)-1H-indole

HRID 2087643Notes

Reaction equation

HRID 2087643 reaction equation
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:11]=[C:10]2[C:6]([CH:7]=[CH:8][NH:9]2)=[CH:5][CH:4]=1.I[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[C:15]1([N:9]2[C:10]3[C:6](=[CH:5][CH:4]=[C:3]([C:2]([F:1])([F:12])[F:13])[CH:11]=3)[CH:7]=[CH:8]2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 11575IodobenzeneHCID 27775236-(Trifluoromethyl)indole

Product 1

HCID 220491711-Phenyl-6-(trifluoromethyl)-1H-indole

Procedure

Prepared by Procedure C and Scheme O using 6-(trifluoromethyl)-1H-indole and iodobenzene: ESMS m/e: 262.0 (M+H)+.

Workup

  1. customPrepared by Procedure C and Scheme O

Sources & evidence

ORD record
ord-7e6939179fa14b8896afe4a0aa5e0605
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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