6-Bromoindole → 6-(2-fluorophenyl)-1H-indole

HRID 2087670Notes

Reaction equation

HRID 2087670 reaction equation
Br[C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[CH:4][CH:3]=1.[F:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1B(O)O>>[F:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6764936-BromoindoleHCID 27343542-Fluorophenylboronic acid

Product 1

HCID 220490006-(2-fluorophenyl)-1H-indole

Procedure

Prepared by Procedure I and Scheme T using 6-bromo-1H-indole and 2-fluorophenylboronic acid: ESMS m/e: 211.9 (M+H)+.

Workup

  1. customPrepared by Procedure I and Scheme T

Sources & evidence

ORD record
ord-f3906b6b04834e4db0a80551400705c8
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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