3-(4-Fluorobenzoyl)propyl chloride → HCID 22049298, compound

HRID 2087678Notes

Reaction equation

HRID 2087678 reaction equation
Cl[CH2:2][CH2:3][CH2:4][C:5]([C:7]1[CH:12]=[CH:11][C:10]([F:13])=[CH:9][CH:8]=1)=[O:6].[NH:14]1[CH2:19][CH2:18][CH:17]([C:20]2[CH:21]=[C:22]([NH:26][C:27](=[O:30])[CH2:28][CH3:29])[CH:23]=[CH:24][CH:25]=2)[CH2:16][CH2:15]1>>[F:13][C:10]1[CH:11]=[CH:12][C:7]([C:5](=[O:6])[CH2:4][CH2:3][CH2:2][N:14]2[CH2:19][CH2:18][CH:17]([C:20]3[CH:21]=[C:22]([NH:26][C:27](=[O:30])[CH2:28][CH3:29])[CH:23]=[CH:24][CH:25]=3)[CH2:16][CH2:15]2)=[CH:8][CH:9]=1

Participants

3

Reactant 2

HCID 197503-(4-Fluorobenzoyl)propyl chlorideHCID 22048836N-[3-(4-Piperidinyl)phenyl]propanamide

Product 1

HCID 22049298HCID 22049298, compound

Procedure

Prepared by Procedure K and Scheme B1 using 4-chloro-1-(4-fluorophenyl)-1-butanone and N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 397.2 (M+H)+.

Workup

  1. customPrepared by Procedure K and Scheme B1

Sources & evidence

ORD record
ord-7520bcfcc9c147b39d92fdd10cfb679e
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

Loading…