4-Chloro-4'-isopropylbutyrophenone → N-(3-{1-[4-(4-Isopropylphenyl)-4-oxobutyl]-4-piperidinyl}phenyl)propanamide

HRID 2087683노트

반응식

HRID 2087683 반응식
Cl[CH2:2][CH2:3][CH2:4][C:5]([C:7]1[CH:12]=[CH:11][C:10]([CH:13]([CH3:15])[CH3:14])=[CH:9][CH:8]=1)=[O:6].[NH:16]1[CH2:21][CH2:20][CH:19]([C:22]2[CH:23]=[C:24]([NH:28][C:29](=[O:32])[CH2:30][CH3:31])[CH:25]=[CH:26][CH:27]=2)[CH2:18][CH2:17]1>>[CH:13]([C:10]1[CH:11]=[CH:12][C:7]([C:5](=[O:6])[CH2:4][CH2:3][CH2:2][N:16]2[CH2:21][CH2:20][CH:19]([C:22]3[CH:23]=[C:24]([NH:28][C:29](=[O:32])[CH2:30][CH3:31])[CH:25]=[CH:26][CH:27]=3)[CH2:18][CH2:17]2)=[CH:8][CH:9]=1)([CH3:15])[CH3:14]

참가 물질

3

반응물 2

HCID 987444-Chloro-4'-isopropylbutyrophenoneHCID 22048836N-[3-(4-Piperidinyl)phenyl]propanamide

생성물 1

HCID 22048668N-(3-{1-[4-(4-Isopropylphenyl)-4-oxobutyl]-4-piperidinyl}phenyl)propanamide

실험 절차

Prepared by Procedure K and Scheme B1 using 4-chloro-1-(4-isopropylphenyl)-1-butanone and N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 421.3 (M+H)+.

후처리

  1. customPrepared by Procedure K and Scheme B1

출처 및 근거

ORD 기록
ord-250801b9dbe542efb17bdaf83cef3139
출처 데이터셋
uspto-grants-2004_04
특허 번호
US06727264B1

반응 노트

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