4'-tert-Butyl-4-chlorobutyrophenone → HCID 22048655, compound

HRID 2087684Notes

Reaction equation

HRID 2087684 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11](=[O:16])[CH2:12][CH2:13][CH2:14]Cl)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[NH:17]1[CH2:22][CH2:21][CH:20]([C:23]2[CH:24]=[C:25]([NH:29][C:30]([CH:32]3[CH2:34][CH2:33]3)=[O:31])[CH:26]=[CH:27][CH:28]=2)[CH2:19][CH2:18]1>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11](=[O:16])[CH2:12][CH2:13][CH2:14][N:17]2[CH2:22][CH2:21][CH:20]([C:23]3[CH:24]=[C:25]([NH:29][C:30]([CH:32]4[CH2:33][CH2:34]4)=[O:31])[CH:26]=[CH:27][CH:28]=3)[CH2:19][CH2:18]2)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 27236944'-tert-Butyl-4-chlorobutyrophenoneHCID 22048669N-[3-(4-Piperidinyl)phenyl]cyclopropanecarboxamide

Product 1

HCID 22048655HCID 22048655, compound

Procedure

Prepared by Procedure K and Scheme B using 1-(4-tert-butylphenyl)-4-chloro-1-butanone and N-[3-(4-piperidinyl)phenyl]cyclopropanecarboxamide: ESMS m/e: 447.2 (M+H)+.

Workup

  1. customPrepared by Procedure K and Scheme B

Sources & evidence

ORD record
ord-f4add1c3d7db401da9640164c9185fb6
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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