5-Chloro-1-oxo-1-(4-trifluoromethylphenyl)pentane → N-[3-(1-{5-Oxo-5-[4-(trifluoromethyl)phenyl]pentyl}-4-piperidinyl)phenyl]propanamide

HRID 2087693노트

반응식

HRID 2087693 반응식
Cl[CH2:2][CH2:3][CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=1)=[O:7].[NH:18]1[CH2:23][CH2:22][CH:21]([C:24]2[CH:25]=[C:26]([NH:30][C:31](=[O:34])[CH2:32][CH3:33])[CH:27]=[CH:28][CH:29]=2)[CH2:20][CH2:19]1>>[O:7]=[C:6]([C:8]1[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=1)[CH2:5][CH2:4][CH2:3][CH2:2][N:18]1[CH2:23][CH2:22][CH:21]([C:24]2[CH:25]=[C:26]([NH:30][C:31](=[O:34])[CH2:32][CH3:33])[CH:27]=[CH:28][CH:29]=2)[CH2:20][CH2:19]1

참가 물질

3

반응물 2

HCID 127094795-Chloro-1-oxo-1-(4-trifluoromethylphenyl)pentaneHCID 22048836N-[3-(4-Piperidinyl)phenyl]propanamide

생성물 1

HCID 22048988N-[3-(1-{5-Oxo-5-[4-(trifluoromethyl)phenyl]pentyl}-4-piperidinyl)phenyl]propanamide

실험 절차

Prepared by Procedure K and Scheme B1 using 5-chloro-1-[4-(trifluoromethyl)phenyl]-1-pentanone and N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 461.2 (M+H)+.

후처리

  1. customPrepared by Procedure K and Scheme B1

출처 및 근거

ORD 기록
ord-70e7fb84b6514ad987e248f70b5397b8
출처 데이터셋
uspto-grants-2004_04
특허 번호
US06727264B1

반응 노트

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