5-Chlorovaleryl chloride → 3-(5-Chloropentanoyl)-4-(3,4-difluorophenyl)-1,3-oxazolidin-2-one

HRID 2087715Notes

Reaction equation

HRID 2087715 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:9]2[CH2:13][O:12][C:11](=[O:14])[NH:10]2)[CH:5]=[CH:6][C:7]=1[F:8].[Cl:15][CH2:16][CH2:17][CH2:18][CH2:19][C:20](Cl)=[O:21]>>[Cl:15][CH2:16][CH2:17][CH2:18][CH2:19][C:20]([N:10]1[CH:9]([C:4]2[CH:5]=[CH:6][C:7]([F:8])=[C:2]([F:1])[CH:3]=2)[CH2:13][O:12][C:11]1=[O:14])=[O:21]

Participants

3

Reactant 2

HCID 740895-Chlorovaleryl chlorideHCID 220487464-(3,4-Difluorophenyl)-1,3-oxazolidin-2-one

Product 1

HCID 220492193-(5-Chloropentanoyl)-4-(3,4-difluorophenyl)-1,3-oxazolidin-2-one

Procedure

Prepared by Procedure AF and Scheme H using 4-(3,4-difluorophenyl)-1,3-oxazolidin-2-one and 5-chloropentanoyl chloride.

Workup

  1. customPrepared by Procedure AF and Scheme H

Sources & evidence

ORD record
ord-6839cd8562684e26be16d9e8327b2882
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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