1-Bromo-5-chloropentane → 3-(5-Chloropentyl)-4-(3,4-difluorophenyl)-1,3-oxazolidin-2-one

HRID 2087716Notes

Reaction equation

HRID 2087716 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:9]2[CH2:13][O:12][C:11](=[O:14])[NH:10]2)[CH:5]=[CH:6][C:7]=1[F:8].Br[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][Cl:21]>>[Cl:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][N:10]1[CH:9]([C:4]2[CH:5]=[CH:6][C:7]([F:8])=[C:2]([F:1])[CH:3]=2)[CH2:13][O:12][C:11]1=[O:14]

Participants

3

Reactant 2

HCID 960701-Bromo-5-chloropentaneHCID 220487464-(3,4-Difluorophenyl)-1,3-oxazolidin-2-one

Product 1

HCID 220490853-(5-Chloropentyl)-4-(3,4-difluorophenyl)-1,3-oxazolidin-2-one

Procedure

Prepared by Procedure G and Scheme C1 using 4-(3,4-difluorophenyl)-1,3-oxazolidin-2-one and 1-bromo-5-chloropentane.

Workup

  1. customPrepared by Procedure G and Scheme C1

Sources & evidence

ORD record
ord-00eaab7358fc437ea8d30aa480c8f15c
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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