2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → HCID 58651270, compound
Reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][C:6]([N:8]1[C@H:12]([C:13]2[CH:18]=[CH:17][C:16]([F:19])=[C:15]([F:20])[CH:14]=2)[CH2:11][O:10][C:9]1=[O:21])=[O:7].[CH3:22][CH:23]([CH3:39])[C:24]([NH:26][C:27]1[CH:32]=[CH:31][CH:30]=[C:29]([CH:33]2[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]2)[CH:28]=1)=[O:25]>>[F:20][C:15]1[CH:14]=[C:13]([C@@H:12]2[CH2:11][O:10][C:9](=[O:21])[N:8]2[C:6](=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2][N:36]2[CH2:37][CH2:38][CH:33]([C:29]3[CH:28]=[C:27]([NH:26][C:24](=[O:25])[CH:23]([CH3:22])[CH3:39])[CH:32]=[CH:31][CH:30]=3)[CH2:34][CH2:35]2)[CH:18]=[CH:17][C:16]=1[F:19]Participants
3
Procedure
Prepared by Procedure G and Scheme B1 using (4R)-3-(5-chloropentanoyl)-4-(3,4-difluorophenyl)-1,3-oxazolidin-2-one and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 528.2 (M+H)+.
Workup
- customPrepared by Procedure G and Scheme B1
Sources & evidence
- ORD record
- ord-248e9f9604ca4ef5ae2920a01de894ee
- Source dataset
- uspto-grants-2004_04
- Patent number
- US06727264B1
Reaction notes
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