[(4-Chlorobutyl)sulfanyl]benzene → N-(3-{1-[4-(Phenylsulfanyl)butyl]-4-piperidinyl}phenyl)cyclopropanecarboxamide

HRID 2087726Notes

Reaction equation

HRID 2087726 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][S:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[NH:13]1[CH2:18][CH2:17][CH:16]([C:19]2[CH:20]=[C:21]([NH:25][C:26]([CH:28]3[CH2:30][CH2:29]3)=[O:27])[CH:22]=[CH:23][CH:24]=2)[CH2:15][CH2:14]1>>[C:7]1([S:6][CH2:5][CH2:4][CH2:3][CH2:2][N:13]2[CH2:18][CH2:17][CH:16]([C:19]3[CH:20]=[C:21]([NH:25][C:26]([CH:28]4[CH2:29][CH2:30]4)=[O:27])[CH:22]=[CH:23][CH:24]=3)[CH2:15][CH2:14]2)[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 13107770[(4-Chlorobutyl)sulfanyl]benzeneHCID 22048669N-[3-(4-Piperidinyl)phenyl]cyclopropanecarboxamide

Product 1

HCID 22049562N-(3-{1-[4-(Phenylsulfanyl)butyl]-4-piperidinyl}phenyl)cyclopropanecarboxamide

Procedure

Prepared by Procedure G and Scheme B1 using [(4-chlorobutyl)sulfanyl]benzene and N-[3-(4-piperidinyl)phenyl]cyclopropanecarboxamide: ESMS m/e: 409.5 (M+H)+.

Workup

  1. customPrepared by Procedure G and Scheme B1

Sources & evidence

ORD record
ord-62e2972a40b94ba8aaab8958789c8a21
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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