[(4-Chlorobutyl)sulfanyl]benzene → 2-Methyl-N-(3-{1-[4-(phenylsulfanyl)butyl]-4-piperidinyl}phenyl)propanamide

HRID 2087727Notes

Reaction equation

HRID 2087727 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][S:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[CH3:13][CH:14]([CH3:30])[C:15]([NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)[CH:19]=1)=[O:16]>>[CH3:13][CH:14]([CH3:30])[C:15]([NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]2[CH2:29][CH2:28][N:27]([CH2:2][CH2:3][CH2:4][CH2:5][S:6][C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=3)[CH2:26][CH2:25]2)[CH:19]=1)=[O:16]

Participants

3

Reactant 2

HCID 13107770[(4-Chlorobutyl)sulfanyl]benzeneHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 220494692-Methyl-N-(3-{1-[4-(phenylsulfanyl)butyl]-4-piperidinyl}phenyl)propanamide

Procedure

Prepared by Procedure G and Scheme B1 using [(4-chlorobutyl)sulfanyl]benzene and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 410.6 (M+H)+.

Workup

  1. customPrepared by Procedure G and Scheme B1

Sources & evidence

ORD record
ord-cf62f5b287124e5dae45cda191645933
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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