2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → HCID 22048901, compound

HRID 2087748Notes

Reaction equation

HRID 2087748 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([CH2:10][CH2:11][CH2:12]Cl)=[O:9].[CH3:14][CH:15]([CH3:31])[C:16]([NH:18][C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([CH:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)[CH:20]=1)=[O:17]>>[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([CH2:10][CH2:11][CH2:12][N:28]1[CH2:29][CH2:30][CH:25]([C:21]2[CH:20]=[C:19]([NH:18][C:16](=[O:17])[CH:15]([CH3:14])[CH3:31])[CH:24]=[CH:23][CH:22]=2)[CH2:26][CH2:27]1)=[O:9]

Participants

3

Reactant 2

HCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 22048739HCID 22048739, compound

Product 1

HCID 22048901HCID 22048901, compound

Procedure

Prepared by Procedure G and Scheme B1 using 1-bromo-2-[(3-chloropropyl)sulfinyl]benzene and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: Anal. Calcd for C24H31BrN2O2S+0.3CHCl3: ESMS m/e: 491.0 (M+H)+.

Workup

  1. customPrepared by Procedure G and Scheme B1

Sources & evidence

ORD record
ord-aaa05d99ec3c48ca98543c81c9d0fdb1
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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