HRID2087779

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21957249

未命名化合物

结构：CC1=C(C(=O)O)C(c2ccc(F)c(F)c2)CC(=O)N1

HCID22048670

4-(3,4-Difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylic acid

C13H11F2NO3

PRODUCTS

生成物

结构：CC(=O)Nc1cccc(C2CCN(CCCNC(=O)C3=C(C)NC(=O)CC3c3ccc(F)c(F)c3)CC2)c1

HCID22725360

未命名化合物

PROCEDURE

实验过程

Prepared by Procedure AC and Scheme AM using N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}acetamide and 4-(3,4-difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxylic acid: ESMS m/e: 525.2 (M+H)+.

WORKUP

后处理

customPrepared by Procedure AC and Scheme

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f236b729af274560803299e1bc19fc31
来源数据集: uspto-grants-2004_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06727264B1
来源说明: uspto-grants-2004_04

反应 SMILES

[NH2:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][CH:8]([C:11]2[CH:12]=[C:13]([NH:17][C:18](=[O:20])[CH3:19])[CH:14]=[CH:15][CH:16]=2)[CH2:7][CH2:6]1.[F:21][C:22]1[CH:23]=[C:24]([CH:29]2[CH2:34][C:33](=[O:35])[NH:32][C:31]([CH3:36])=[C:30]2[C:37](O)=[O:38])[CH:25]=[CH:26][C:27]=1[F:28]>>[C:18]([NH:17][C:13]1[CH:12]=[C:11]([CH:8]2[CH2:9][CH2:10][N:5]([CH2:4][CH2:3][CH2:2][NH:1][C:37]([C:30]3[CH:29]([C:24]4[CH:25]=[CH:26][C:27]([F:28])=[C:22]([F:21])[CH:23]=4)[CH2:34][C:33](=[O:35])[NH:32][C:31]=3[CH3:36])=[O:38])[CH2:6][CH2:7]2)[CH:16]=[CH:15][CH:14]=1)(=[O:20])[CH3:19]