HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Nitrophenyl)-5-(trifluoromethyl)pyrazole-4-carbonyl chloride → N-(6-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}hexyl)-1-(4-nitrophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Nitrophenyl)-5-(trifluoromethyl)pyrazole-4-carbonyl chloride | HCID 2775746 | — |
| Reactant | N-{3-[1-(6-Aminohexyl)4-piperidinyl]phenyl}-2-methylpropanamide | HCID 16755868 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-(6-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}hexyl)-1-(4-nitrophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide | HCID 22049026 | — |
Reaction Steps
Prepared by Procedure Q1 (THF) and Scheme AT using N-{3-[1-(6-aminohexyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 1-(4-nitrophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carbonyl chloride: ESMS m/e: 629.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727264B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-9ca9976f74884bffaa77c5fd16731cc1 |
| Source note | uspto-grants-2004_04 |