HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-4-(propane-2-sulfonyl)-thiophene-2-carbonyl chloride → 3-Chloro-N-(6-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}hexyl)-4-(isopropylsulfonyl)-2-thiophenecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-4-(propane-2-sulfonyl)-thiophene-2-carbonyl chloride | HCID 2778695 | — |
| Reactant | N-{3-[1-(6-Aminohexyl)4-piperidinyl]phenyl}-2-methylpropanamide | HCID 16755868 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Chloro-N-(6-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}hexyl)-4-(isopropylsulfonyl)-2-thiophenecarboxamide | HCID 22049587 | — |
Reaction Steps
Prepared by Procedure Q1 (THF) and Scheme AT using N-{3-[1-(6-aminohexyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 3-chloro-4-(isopropylsulfonyl)-2-thiophenecarbonyl chloride: ESMS m/e: 596.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727264B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-e701d52f26bd47ab88cf754634266208 |
| Source note | uspto-grants-2004_04 |