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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087811Generated: October 26, 2026

3,5-Dichlorobenzoyl chloride → 3,5-Dichloro-N-(4-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}butyl)benzamide

https://huagongshe.com/reaction/2087811

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Dichlorobenzoyl chlorideHCID 76191—
ReactantN-{3-[1-(4-Aminobutyl)4-piperidinyl]phenyl}-2-methylpropanamideHCID 16757471—
SolventTetrahydrofurane dichloromethaneHCID 21919333—
Product3,5-Dichloro-N-(4-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}butyl)benzamideHCID 22048745—

Reaction Steps

Prepared by Procedure Q2 (THF/DCM, 1:3) and Scheme AT using N-{3-[1-(4-aminobutyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 3,5-dichlorobenzoyl chloride: ESMS m/e: 490.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-9250e18152704876b5c9cf14fa13d203
Source noteuspto-grants-2004_04