3,5-Dichlorophenyl isocyanate → HCID 22049086, compound

HRID 2087815Notes

Reaction equation

HRID 2087815 reaction equation
[CH:1]([NH:3][CH2:4][CH2:5][CH2:6][CH2:7][N:8]1[CH2:13][CH2:12][CH:11]([C:14]2[CH:15]=[C:16]([NH:20][C:21](=[O:25])[CH:22]([CH3:24])[CH3:23])[CH:17]=[CH:18][CH:19]=2)[CH2:10][CH2:9]1)=[O:2].[Cl:26][C:27]1[CH:28]=[C:29]([N:34]=C=O)[CH:30]=[C:31]([Cl:33])[CH:32]=1>C1COCC1.C(Cl)Cl>[Cl:26][C:27]1[CH:28]=[C:29]([CH:30]=[C:31]([Cl:33])[CH:32]=1)[NH:34][C:1]([NH:3][CH2:4][CH2:5][CH2:6][CH2:7][N:8]1[CH2:13][CH2:12][CH:11]([C:14]2[CH:15]=[C:16]([NH:20][C:21](=[O:25])[CH:22]([CH3:23])[CH3:24])[CH:17]=[CH:18][CH:19]=2)[CH2:10][CH2:9]1)=[O:2]

Participants

4

Reactant 2

HCID 944603,5-Dichlorophenyl isocyanateHCID 22049400HCID 22049400, compound

Product 1

HCID 22049086HCID 22049086, compound

Reagents, catalysts & solvents 1

HCID 21919333Tetrahydrofurane dichloromethaneSolvent

Procedure

Prepared by Procedure Q2 (THF/DCM, 1:3) and Scheme AT using N-(3-{1-[4-(formylamino)butyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 3,5-dichlorophenyl isocyanate: ESMS m/e: 505.0 (M+H)+.

Sources & evidence

ORD record
ord-ae909c321df14aa9858b50ebddb5634f
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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