4-Biphenylyl isocyanate → HCID 22049047, compound

HRID 2087816Notes

Reaction equation

HRID 2087816 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][N:6]1[CH2:11][CH2:10][CH:9]([C:12]2[CH:13]=[C:14]([NH:18][C:19](=[O:23])[CH:20]([CH3:22])[CH3:21])[CH:15]=[CH:16][CH:17]=2)[CH2:8][CH2:7]1.[CH:24]1[CH:29]=[CH:28][C:27]([C:30]2[CH:35]=[CH:34][C:33]([N:36]=[C:37]=[O:38])=[CH:32][CH:31]=2)=[CH:26][CH:25]=1>C1COCC1.C(Cl)Cl>[C:30]1([C:27]2[CH:26]=[CH:25][CH:24]=[CH:29][CH:28]=2)[CH:31]=[CH:32][C:33]([NH:36][C:37]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][N:6]2[CH2:7][CH2:8][CH:9]([C:12]3[CH:13]=[C:14]([NH:18][C:19](=[O:23])[CH:20]([CH3:21])[CH3:22])[CH:15]=[CH:16][CH:17]=3)[CH2:10][CH2:11]2)=[O:38])=[CH:34][CH:35]=1

Participants

4

Reactant 2

HCID 36123194-Biphenylyl isocyanateHCID 16757471N-{3-[1-(4-Aminobutyl)4-piperidinyl]phenyl}-2-methylpropanamide

Product 1

HCID 22049047HCID 22049047, compound

Reagents, catalysts & solvents 1

HCID 21919333Tetrahydrofurane dichloromethaneSolvent

Procedure

Prepared by Procedure Q2 (THF/DCM, 1:3) and Scheme AT using N-{3-[1-(4-aminobutyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 4-biphenyl isocyanate: ESMS m/e: 513.0 (M+H)+.

Sources & evidence

ORD record
ord-1c495d5fa47e42ff8bec4b95498d7fcb
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

Loading…