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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087835Generated: October 31, 2026

Veratroyl chloride → N-(4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl)-3,4-dimethoxybenzamide

https://huagongshe.com/reaction/2087835

Reaction equation

Participants

RoleNameHCIDCharge
ReactantVeratroyl chlorideHCID 77070—
ReactantN-{3-[1-(4-Aminobutyl)4-piperidinyl]phenyl}-2-methylpropanamideHCID 16757471—
SolventTetrahydrofurane dichloromethaneHCID 21919333—
ProductN-(4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl)-3,4-dimethoxybenzamideHCID 22049467—

Reaction Steps

Prepared by Procedure Q2 (THF/DCM, 1:3) and Scheme AT using N-{3-[1-(4-aminobutyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 3,4-dimethoxybenzoyl chloride: ESMS m/e: 482.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-6024c2ef6b61444fa00f6cf8abd20675
Source noteuspto-grants-2004_04