HRID2087840

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10738

1,1-Diphenylhydrazine hydrochloride

C12H13ClN2

结构：CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccc(C(F)(F)F)cc3)CC2)c1

HCID22049207

未命名化合物

PRODUCTS

生成物

结构：CC(C)C(=O)Nc1cccc(C2CCN(CCCc3c(-c4ccc(C(F)(F)F)cc4)n(-c4ccccc4)c4ccccc34)CC2)c1

HCID22049067

未命名化合物

PROCEDURE

实验过程

Prepared by Procedure E and Scheme M using 2-methyl-N-[3-(1-{5-oxo-5-[4-(trifluoromethyl)phenyl]pentyl}-4-piperidinyl)phenyl]propanamide and 1,1-diphenylhydrazine hydrochloride: ESMS m/e: 624.2 (M+H)+.

WORKUP

后处理

customPrepared by Procedure E and Scheme M

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5eb26ac3e4f14dc8924cb50d7fc1845e
来源数据集: uspto-grants-2004_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06727264B1
来源说明: uspto-grants-2004_04

反应 SMILES

[CH3:1][CH:2]([CH3:34])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][CH2:21][C:22](=O)[C:23]3[CH:28]=[CH:27][C:26]([C:29]([F:32])([F:31])[F:30])=[CH:25][CH:24]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4].Cl.[C:36]1([N:42]([C:44]2[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=2)N)[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1>>[CH3:1][CH:2]([CH3:34])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][C:21]3[C:37]4[C:36](=[CH:41][CH:40]=[CH:39][CH:38]=4)[N:42]([C:44]4[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=4)[C:22]=3[C:23]3[CH:24]=[CH:25][C:26]([C:29]([F:30])([F:32])[F:31])=[CH:27][CH:28]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4]