3-(3',4'-Dimethoxyphenyl)-1-propanol → N-(3-{1-[3-(3,4-Dimethoxyphenyl)propyl]-4-piperidinyl}phenyl)-2-methylpropanamide

HRID 2087953Notes

Reaction equation

HRID 2087953 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][CH2:12][CH2:13]O)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[CH3:15][CH:16]([CH3:32])[C:17]([NH:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)[CH:21]=1)=[O:18]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][CH2:12][CH2:13][N:29]2[CH2:30][CH2:31][CH:26]([C:22]3[CH:21]=[C:20]([NH:19][C:17](=[O:18])[CH:16]([CH3:15])[CH3:32])[CH:25]=[CH:24][CH:23]=3)[CH2:27][CH2:28]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

3

Reactant 2

HCID 775283-(3',4'-Dimethoxyphenyl)-1-propanolHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 22049258N-(3-{1-[3-(3,4-Dimethoxyphenyl)propyl]-4-piperidinyl}phenyl)-2-methylpropanamide

Procedure

Prepared by Procedure O and Scheme W using 3-(3,4-dimethoxyphenyl)-1-propanol and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 425.2 (M+H)+.

Workup

  1. customPrepared by Procedure O and Scheme W

Sources & evidence

ORD record
ord-369be27f01294dbfb024b427dc35b579
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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