1-Methylindole-2-carboxaldehyde → HCID 22049191, compound

HRID 2087969Notes

Reaction equation

HRID 2087969 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]1[CH:11]=O.[CH3:13][CH:14]([CH3:30])[C:15]([NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)[CH:19]=1)=[O:16]>CC(O)=O>[CH3:13][CH:14]([CH3:30])[C:15]([NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]2[CH2:29][CH2:28][N:27]([CH2:11][C:3]3[N:2]([CH3:1])[C:10]4[C:5]([CH:4]=3)=[CH:6][CH:7]=[CH:8][CH:9]=4)[CH2:26][CH2:25]2)[CH:19]=1)=[O:16]

Participants

4

Reactant 2

HCID 2671641-Methylindole-2-carboxaldehydeHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 22049191HCID 22049191, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Prepared by Procedure F and Scheme R, without HOAc, using 1-methyl-1H-indole-2-carbaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 390.3 (M+H)+.

Sources & evidence

ORD record
ord-696f8665dca542bdb183f231f2be2ef0
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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