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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087979Generated: October 26, 2026

o-Iodoanisole → N-[3-(1-{[1-(2-Methoxyphenyl)-1H-indol-5-YL]methyl}-4-piperidinyl)phenyl]-2-methylpropanamide

https://huagongshe.com/reaction/2087979

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-IodoanisoleHCID 68257—
ReactantN-{3-[1-(1H-indol-5-ylmethyl)-4-piperidinyl]phenyl)-2-methylpropanamideHCID 22049334—
ProductN-[3-(1-{[1-(2-Methoxyphenyl)-1H-indol-5-YL]methyl}-4-piperidinyl)phenyl]-2-methylpropanamideHCID 22049615—

Reaction Steps

Prepared by Procedure C and Scheme Q1, with CuBr in place of Cu, using 1-iodo-2-methoxybenzene and N-{3-[1-(1H-indol-5-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide: ESMS m/e: 482.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-7dcf4abc06324e22a8f426fd8a73b6be
Source noteuspto-grants-2004_04