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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2088000Generated: October 26, 2026

4-Iodo-1,2-dimethylbenzene → N-[3-(1-{[1-(3,4-Dimethylphenyl)-1H-indol-4-YL]methyl}-4-piperidinyl)phenyl]-2-methylpropanamide

https://huagongshe.com/reaction/2088000

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Iodo-1,2-dimethylbenzeneHCID 141646—
ReactantN-(3-[1-(1H-indol-4-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamideHCID 22048637—
ProductN-[3-(1-{[1-(3,4-Dimethylphenyl)-1H-indol-4-YL]methyl}-4-piperidinyl)phenyl]-2-methylpropanamideHCID 22048676—

Reaction Steps

Prepared by Procedure C and Scheme Q1, with CuBr in place of Cu, using N-{3-[1-(1H-indol-4-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 4-iodo-1,2-dimethylbenzene: ESMS m/e: 480.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-71e4bec5d00b492c88c0ea44f7901028
Source noteuspto-grants-2004_04