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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2088008Generated: October 26, 2026

1-Fluoro-2-iodobenzene → N-[3-(1-{[1-(2-Fluorophenyl)-1H-indol-4-YL]methyl}-4-piperidinyl)phenyl]-2-methylpropanamide

https://huagongshe.com/reaction/2088008

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Fluoro-2-iodobenzeneHCID 67673—
ReactantN-(3-[1-(1H-indol-4-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamideHCID 22048637—
ProductN-[3-(1-{[1-(2-Fluorophenyl)-1H-indol-4-YL]methyl}-4-piperidinyl)phenyl]-2-methylpropanamideHCID 22049391—

Reaction Steps

Prepared by Procedure C and Scheme Q1, with CuBr in place of Cu, using 1-fluoro-2-iodobenzene and N-{3-[1-(1H-indol-4-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide: ESMS m/e: 470.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-e0881fdbeae7424cad4aa6989e46377c
Source noteuspto-grants-2004_04