HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-iodo-2-(trifluoromethyl)- → 2-Methyl-N-(3-[1-({1-[2-(trifluoromethyl)phenyl]-1H-indol-4-YL}methyl)-4-piperidinyl]phenyl}propanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-iodo-2-(trifluoromethyl)- | HCID 67957 | — |
| Reactant | N-(3-[1-(1H-indol-4-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide | HCID 22048637 | — |
| Product | 2-Methyl-N-(3-[1-({1-[2-(trifluoromethyl)phenyl]-1H-indol-4-YL}methyl)-4-piperidinyl]phenyl}propanamide | HCID 22725378 | — |
Reaction Steps
Prepared by Procedure C and Scheme Q1, with CuBr in place of Cu, using 1-iodo-2-(trifluoromethyl)benzene and N-{3-[1-(1H-indol-4-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide: ESMS m/e: 520.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727264B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-58aff5d98e364177aa33e02d8547633e |
| Source note | uspto-grants-2004_04 |