2,3-Dimethyliodobenzene → HCID 22049175, compound

HRID 2088015Notes

Reaction equation

HRID 2088015 reaction equation
I[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[CH3:9].[NH:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][C:17]=2[CH2:19][N:20]2[CH2:25][CH2:24][CH:23]([C:26]3[CH:27]=[C:28]([NH:32][C:33](=[O:37])[CH:34]([CH3:36])[CH3:35])[CH:29]=[CH:30][CH:31]=3)[CH2:22][CH2:21]2)[CH:12]=[CH:11]1>>[CH3:9][C:3]1[C:4]([CH3:8])=[CH:5][CH:6]=[CH:7][C:2]=1[N:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][C:17]=2[CH2:19][N:20]2[CH2:21][CH2:22][CH:23]([C:26]3[CH:27]=[C:28]([NH:32][C:33](=[O:37])[CH:34]([CH3:35])[CH3:36])[CH:29]=[CH:30][CH:31]=3)[CH2:24][CH2:25]2)[CH:12]=[CH:11]1

Participants

3

Reactant 2

HCID 1416452,3-DimethyliodobenzeneHCID 22048591HCID 22048591, compound

Product 1

HCID 22049175HCID 22049175, compound

Procedure

Prepared by Procedure C and Scheme Q1, with CuBr in place of Cu, using 1-iodo-2,3-dimethylbenzene and N-{3-[1-(1H-indol-7-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide: ESMS m/e: 480.0 (M+H)+.

Sources & evidence

ORD record
ord-1383c470c8ef4d8e9c9e94ebf1cb370f
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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