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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2088016Generated: November 1, 2026

5-Chloro-1-oxo-1-(4-trifluoromethylphenyl)pentane → 2-Methyl-N-[3-(1-(5-oxo-5-[4-(trifluoromethyl)phenyl]pentyl}-4-piperidinyl)phenyl]propanamide

https://huagongshe.com/reaction/2088016

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-1-oxo-1-(4-trifluoromethylphenyl)pentaneHCID 12709479—
Reactant2-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 16757255—
Product2-Methyl-N-[3-(1-(5-oxo-5-[4-(trifluoromethyl)phenyl]pentyl}-4-piperidinyl)phenyl]propanamideHCID 22049207—

Reaction Steps

Prepared by Procedure K and Scheme E using 5-chloro-1-[4-(trifluoromethyl)phenyl]-1-pentanone and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 475.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-08d45717662641689f14d18432e7641a
Source noteuspto-grants-2004_04