HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → N-(3-{1-(5-(2-fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-methyl-N-[3-(4-piperidyl)phenyl]propanamide | HCID 16757255 | — |
| Reactant | 5-Chloro-1-(2-fluorophenyl)-1-oxopentane | HCID 22048800 | — |
| Product | N-(3-{1-(5-(2-fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamide | HCID 22049199 | — |
Reaction Steps
Prepared by Procedure K and Scheme E using K2CO3 instead of Na2CO3 and NaI instead of KI and 5-chloro-1-(2-fluorophenyl)-1-pentanone and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 425.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727264B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-b3f719bcfd494c33ae0518bd014d2f4e |
| Source note | uspto-grants-2004_04 |