Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2088055Generated: October 31, 2026

2-Fluoro-5-(trifluoromethyl)phenol → N-[3-(1-{6-(3-Fluorophenyl)-6-[2-fluoro-5-(trifluoromethyl)phenoxy]hexyl}-4-piperidinyl)phenyl]-2-methylpropanamide

https://huagongshe.com/reaction/2088055

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)phenolHCID 518888—
ReactantN-(3-{1-[6-(3-fluorophenyl)-6-hydroxyhexyl]-4-piperidinyl)phenyl)-2-methylpropanamideHCID 22048989—
ProductN-[3-(1-{6-(3-Fluorophenyl)-6-[2-fluoro-5-(trifluoromethyl)phenoxy]hexyl}-4-piperidinyl)phenyl]-2-methylpropanamideHCID 22049303—

Reaction Steps

Prepared by Procedure A and Scheme AN using 2-fluoro-5-(trifluoromethyl)phenol and N-(3-{1-[6-(3-fluorophenyl)-6-hydroxyhexyl]-4-piperidinyl}phenyl)-2-methylpropanamide: ESMS m/e: 603.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-2d92de124bc74f06843a365122b028b5
Source noteuspto-grants-2004_04