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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2088071Generated: October 30, 2026

Hydrochloric Acid → HCID 22049479, compound

https://huagongshe.com/reaction/2088071

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant2-Fluoro-5-(trifluoromethyl)phenolHCID 518888—
ReactantHCID 22049157HCID 22049157—
ProductHCID 22049479HCID 22049479—

Reaction Steps

Prepared by Procedure A and Scheme AN using 2-fluoro-5-(trifluoromethyl)phenol and N-(3-{1-[5-(2-fluorophenyl)-5-hydroxypentyl]-4-piperidinyl}phenyl)-2-methylpropanamide: 1H NMR (400 MHz, CDCl3), HCl salt δ 7.89 (s, br, 1H), 7.72-6.88 (m, 11H), 5.59-5.48 (m, 1H), 3.70-3.48 (br, 2H), 3.05-2.84 (br, 2H), 2.82-2.58 (m, br, 4H), 2.58-2.40 (m, br, 2H), 2.22-1.82 (m, br, 6H), 1.71-1.42 (m, br, 2H), 1.25 (d, 6H, J=6.4 Hz); ESMS m/e: 589.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-ed25ff531b8d433dae6ce8c3dd17e183
Source noteuspto-grants-2004_04