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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2088074Generated: October 31, 2026

Hydrochloric Acid → HCID 22049093, compound

https://huagongshe.com/reaction/2088074

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant2-Fluoro-5-(trifluoromethyl)phenolHCID 518888—
ReactantHCID 22048764HCID 22048764—
ProductHCID 22049093HCID 22049093—

Reaction Steps

Prepared by Procedure A and Scheme AN using 2-fluoro-5-(trifluoromethyl)phenol and N-(3-{1-[5-(4-chlorophenyl)-5-hydroxypentyl]-4-piperidinyl}phenyl)-2-methylpropanamide: 1H NMR (400 MHz, CDCl3), HCl salt δ 7.61-6.92 (m, 11H), 5.24-5.16 (m, 1H), 3.70-3.58 (m, 2H), 3.02-2.91 (br, 2H), 2.80-2.64 (m, br, 3H), 2.64-2.50 (m, 3H), 2.18-1.94 (m, br, 6H), 1.62-1.44 (m, br, 2H), 1.25 (d, 6H, J=7.2 Hz); ESMS m/e: 605.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-cb6158281c9b4d0cb8d0facb5b09eff6
Source noteuspto-grants-2004_04