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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2088254Generated: November 1, 2026

N-Phthaloylglycine → 2H-Isoindole-2-acetyl chloride, 1,3-dihydro-1,3-dioxo-

https://huagongshe.com/reaction/2088254

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-PhthaloylglycineHCID 20825—
ReactantThionyl ChlorideHCID 24386—
Product2H-Isoindole-2-acetyl chloride, 1,3-dihydro-1,3-dioxo-HCID 81242—

Reaction Steps

(G2) adding SOCl2 to the compound 1 of step (G1) to produce 2-(1,3-dioxoisoindolin-2-yl)acetic chloride (compound 2);

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08435480B2
Source datasetuspto-grants-2013_05
ORD IDord-68a7d918011b406eabe1a93d75aabf8e
Source noteuspto-grants-2013_05