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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2088309Generated: November 2, 2026

Indole-3-pyruvic acid → Monatin

https://huagongshe.com/reaction/2088309

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndole-3-pyruvic acidHCID 803—
ReactantL-AlanineHCID 5950—
ProductMonatinHCID 9860847—

Reaction Steps

The addition of alanine to indole-3-pyruvic acid produces monatin, and this reaction can be performed synthetically with a Grignard or organolithium reagent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08435765B2
Source datasetuspto-grants-2013_05
ORD IDord-7eaf325088af4658a3606bad288442a6
Source noteuspto-grants-2013_05