HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Trifluoromethyl)nicotinic acid → HCID 45381524, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Trifluoromethyl)nicotinic acid | HCID 2777551 | — |
| Reactant | HCID 44286533 | HCID 44286533 | — |
| Product | HCID 45381524 | HCID 45381524 | — |
Reaction Steps
Title compound was synthesized according to the procedure used in the synthesis of Compound 19S, using 6-(trifluoromethyl)nicotinic acid in place of o-methoxybenzoic acid. 1H NMR (400 MHz, CDCl3) S (ppm): 8.84 (s, 1H), 8.34 (dd, J=8 Hz, 1H), 8.23 (s, 1H), 8.12 (dd, J=8 Hz, 1H), 4.18 (m, 1H), 3.39 (ddd, J=10, 14 Hz, 1H), 2.96-2.87 (m, 4H), 2.68 (ddd, J=16 Hz, 1H), 2.06 (m, 1H), 1.82 (m, 1H), 1.74 (m, 1H), 1.55 (m, 1H). C14H16F3N3O=299.12 LCMS (M+H): m/z 300
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08435762B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-1099b276ac4847e98ae1b4519bd6f6ff |
| Source note | uspto-grants-2013_05 |