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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2088319Generated: November 3, 2026

6-(Trifluoromethyl)nicotinic acid → HCID 45381524, compound

https://huagongshe.com/reaction/2088319

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(Trifluoromethyl)nicotinic acidHCID 2777551—
ReactantHCID 44286533HCID 44286533—
ProductHCID 45381524HCID 45381524—

Reaction Steps

Title compound was synthesized according to the procedure used in the synthesis of Compound 19S, using 6-(trifluoromethyl)nicotinic acid in place of o-methoxybenzoic acid. 1H NMR (400 MHz, CDCl3) S (ppm): 8.84 (s, 1H), 8.34 (dd, J=8 Hz, 1H), 8.23 (s, 1H), 8.12 (dd, J=8 Hz, 1H), 4.18 (m, 1H), 3.39 (ddd, J=10, 14 Hz, 1H), 2.96-2.87 (m, 4H), 2.68 (ddd, J=16 Hz, 1H), 2.06 (m, 1H), 1.82 (m, 1H), 1.74 (m, 1H), 1.55 (m, 1H). C14H16F3N3O=299.12 LCMS (M+H): m/z 300

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08435762B2
Source datasetuspto-grants-2013_05
ORD IDord-1099b276ac4847e98ae1b4519bd6f6ff
Source noteuspto-grants-2013_05