反应详情

A solution of (4) (11.4 g, 26.86 mmol) in ethanol (225 ml) containing 1.2 g 20% palladium on activated carbon (50% wet) was hydrogenated at 30 psi for 3 hrs. The catalyst was removed by filtration and the solution was washed with ethanol. The solvent was removed in a rotary evaporator. The residue was dried in a vacuum oven (50° C.) to produce (5) (5.86 g, 75%).

1. customThe catalyst was removed by filtration
2. washthe solution was washed with ethanol
3. customThe solvent was removed in a rotary evaporator
4. customThe residue was dried in a vacuum oven (50° C.)