HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 59534556, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | HCID 59534531 | HCID 59534531 | — |
| Product | HCID 59534556 | HCID 59534556 | — |
Reaction Steps
Analogously to Example 28.5, 6-(3,5-difluorophenyl)-2-[3-(5-piperidin-4-ylthiazol-2-yl)benzyl]-2H-pyridazin-3-one is reacted with formaldehyde and sodium triacetoxyborohydride to give 6-(3,5-difluorophenyl)-2-{3-[5-(1-methylpiperidin-4-yl)thiazol-2-yl]benzyl}-2H-pyridazin-3-one (“A92”), ESI 479.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08435981B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-aa72cb3544864aba84bc5c883852389e |
| Source note | uspto-grants-2013_05 |