反应详情

A mixture of N-methyl-3-(2-nitro-5-phenoxy-benzylamino)-N-phenyl-propionamide (2 g, 0.0049 mol), 10% palladium on carbon (1 g), and thiophene solution (1 mL) in 150 mL of MeOH was hydrogenated until 3 equivalents of hydrogen were consumed. The reaction mixture was filtered, and the filtrate was concentrated. The resulting residue was purified by column chromatography on a Biotage. The product containing fractions were collected and concentrated to yield a residue.

1. customwere consumed
2. filtrationThe reaction mixture was filtered
3. concentrationthe filtrate was concentrated
4. customThe resulting residue was purified by column chromatography on a Biotage
5. additionThe product containing fractions
6. customwere collected
7. concentrationconcentrated
8. customto yield a residue