HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2088846Generated: October 31, 2026
Benzenesulfonyl chloride → HCID 58625117, compound
https://huagongshe.com/reaction/2088846
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | 3-(3-Dimethoxymethyl-4-nitro-phenylsulfanyl)-phenylamine | HCID 58625054 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 58625117 | HCID 58625117 | — |
Reaction Steps
A mixture of 3-(3-dimethoxymethyl-4-nitro-phenylsulfanyl)-phenylamine (0.0384 mol) and TEA (0.0578 mol) in THF (q.s.) was cooled to 5° C., and phenylsulfonyl chloride (0.0384 mol) was added dropwise at 5° C. Then, the reaction mixture was reacted at room temperature, and purified by column chromatography over silica gel (eluent: CH2Cl2). The product fractions were collected and the solvent was evaporated to yield the title compound as a residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08436006B2 |
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| Source dataset | uspto-grants-2013_05 |
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| ORD ID | ord-76454a5c8c99400f82a14104d2fffa0e |
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| Source note | uspto-grants-2013_05 |
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