Sodium Hydroxide → HCID 178458771, compound

Participants

Reaction Steps

A solution of Example 241a (0.056 g, 0.088 mmol) in dioxane (1.5 mL) was treated with 20% sodium hydroxide (0.10 mL, 0.088 mmol). The mixture was heated at 90 C for an hour. The solvent was evaporated. The residue was treated with 20% brine and twice extracted with dichloromethane. The layers were combined, dried with MgSO4 and concentrated to give 0.037 g of the title compound. The crude product was used in the next step without further purification.

Provenance & Evidence