Ammonia → 5-(4-amino-3-methoxyphenyl)-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

HRID 208912Notes

Reaction equation

HRID 208912 reaction equation
[CH2:26]1[O:27][CH2:28][CH2:29][O:30][CH2:31]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH:20]1[CH2:21][CH2:22][CH2:23][CH2:24]1)[cH:9][c:10]2-[c:11]1[cH:12][c:13]([O:18][CH3:19])[c:14]([NH2:15])[cH:16][cH:17]1.[NH3:25]>>[c:2]1([NH2:25])[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH:20]1[CH2:21][CH2:22][CH2:23][CH2:24]1)[cH:9][c:10]2-[c:11]1[cH:12][c:13]([O:18][CH3:19])[c:14]([NH2:15])[cH:16][cH:17]1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 312751,4-DioxaneHCID 541919345-(4-Amino-3-methoxyphenyl)-4-chloro-7-cyclopentylpyrrolo[2,3-d]pyrimidine

Product 1

HCID 539252325-(4-amino-3-methoxyphenyl)-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-8bebf85160c34a238df9ae4f89533b0d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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