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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2089142Generated: October 25, 2026

4-Ethylcyclohexanone → N-[1-(4-Ethyl-cyclohexyl)-azetidin-3-yl]-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide

https://huagongshe.com/reaction/2089142

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-EthylcyclohexanoneHCID 79506—
ReactantN-Azetidin-3-yl-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide TFA saltHCID 86660176—
ProductN-[1-(4-Ethyl-cyclohexyl)-azetidin-3-yl]-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamideHCID 54756151—

Reaction Steps

The title compound was prepared as a white solid from reaction of (N-Azetidin-3-yl-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide TFA salt (as prepared in Example 1, Step D) and 4-ethyl-cyclohexanone using the procedure described in Step E of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08436023B2
Source datasetuspto-grants-2013_05
ORD IDord-15b4523c937845ec862959ae5fd6bedf
Source noteuspto-grants-2013_05