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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2089149Generated: October 30, 2026

Glyoxylic Acid → (1-Methyl-5-trifluoromethyl-1H-indazol-3-ylamino)-acetic acid

https://huagongshe.com/reaction/2089149

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlyoxylic AcidHCID 760—
Reactant1-Methyl-5-(trifluoromethyl)-1H-indazol-3-amineHCID 28875377—
Product(1-Methyl-5-trifluoromethyl-1H-indazol-3-ylamino)-acetic acidHCID 67478753—

Reaction Steps

The title compound was prepared as white solid from reductive amination of 1-methyl-5-trifluoromethyl-1H-indazol-3-ylamine (as prepared in the previous step) and glyoxylic acid using the procedure described in Step B of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08436023B2
Source datasetuspto-grants-2013_05
ORD IDord-8293e9c914924dd5a2f77887b30b5deb
Source noteuspto-grants-2013_05