Allyl bromide → 4-Allyloxymethyl-cyclohexanone

HRID 2089172Notes

Reaction equation

[O:1]1[C:5]2([CH2:10][CH2:9][CH:8]([CH2:11][OH:12])[CH2:7][CH2:6]2)OCC1.[CH2:13](Br)[CH:14]=[CH2:15]>>[CH2:15]([O:12][CH2:11][CH:8]1[CH2:7][CH2:6][C:5](=[O:1])[CH2:10][CH2:9]1)[CH:14]=[CH2:13]

Participants

Reactant 2

HCID 7841Allyl bromide

HCID 100808381,4-Dioxaspiro[4.5]decan-8-ylmethanol

Product 1

HCID 585487714-Allyloxymethyl-cyclohexanone

Procedure

The title compound was prepared as white solid from reaction of (1,4-dioxa-spiro[4.5]dec-8-yl)-methanol and allyl bromide (Aldrich) followed by de-protection using the procedure described in Example 34.

Sources & evidence

ORD record: ord-0d876ffa3349423dae19d61f5c47b8d6
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08436023B2

Reaction notes

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