4-Isopropylcyclohexanone → HCID 54755193, compound

HRID 2089190Notes

Reaction equation

[NH:1]1[CH2:4][CH:3]([NH:5][C:6](=[O:22])[CH2:7][NH:8][C:9]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([C:18]([F:21])([F:20])[F:19])[CH:16]=3)[NH:11][N:10]=2)[CH2:2]1.[CH:23]([CH:26]1[CH2:31][CH2:30][C:29](=O)[CH2:28][CH2:27]1)([CH3:25])[CH3:24]>>[CH:23]([CH:26]1[CH2:31][CH2:30][CH:29]([N:1]2[CH2:2][CH:3]([NH:5][C:6](=[O:22])[CH2:7][NH:8][C:9]3[C:17]4[C:12](=[CH:13][CH:14]=[C:15]([C:18]([F:20])([F:19])[F:21])[CH:16]=4)[NH:11][N:10]=3)[CH2:4]2)[CH2:28][CH2:27]1)([CH3:25])[CH3:24]

Participants

Reactant 2

HCID 794884-Isopropylcyclohexanone

HCID 58548846HCID 58548846, compound

Product 1

HCID 54755193HCID 54755193, compound

Procedure

The title compound was prepared as a white solid from reaction of N-azetidin-3-yl-2-(5-trifluoromethyl-1H-indazol-3-ylamino)-acetamide (as prepared in Example 41, Step A) and 4-isopropyl-cyclohexanone using the procedure described in Step E of Example 1.

Sources & evidence

ORD record: ord-41f9333676ab4d12ba0844ff38b2e211
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08436023B2

Reaction notes

Loading…